Chlorophyllin intervention reduces aflatoxin-DNA adducts in individuals at high risk for liver cancer (Qidong , China).
Egner, P. et al. 2001. Proc. Nat. Acad. Sci. 2001; 98:14601-14606
Residents of the area are at risk of developing hepatocellular carcinoma (liver cancer) partly as a result of ingesting aflatoxin. Chlorophyllin was shown to be an inhibitor of aflatoxin carcinogenesis in animals, so this trial was carried out with 180 adult patients.
Levels of aflatoxin-guanine in urine (associated with increased risk of liver cancer) were found to decrease 55% over a four month period in comparison to placebo. No adverse events were reported.